The closest thing Marie Jensen
Present tense gives your query more immediacy.
Wings for Marie is a 120,000-word religious fantasy
Novels don't share; they tell.
This is very general. You give it specificity in the next sentence. Specific is better than general almost always.
At the age of sixteen, Marie’s drug-riddled defeat and deep depression drives her to commit suicide.
I'm not sure what drug-riddled defeat is. It's more descriptive than abuse, neglect, and heartache but it's still not the most evocative phrase.
Adierenor is so angry at the world that led Marie to kill herself that he decides to embark on a quest for divine retribution.
This sentence doesn't actually work. You'll know that if you take out the clause "Adierenor is so angry at the world that" Without it you have "Led Marie to kill herself that he decides etc."
If a sentence doesn't work without the clause, you need to fix it. It's generally an EVENT that precipitates something, not a person. (A person DOING something, yes, but you see what I mean)
In attempt to obtain a weapon for his future vengeance, he journeys through worlds both familiar and unfamiliar: the slums of Denver, the blue-flamed river of Purgatory, and Hell’s Passage of the Damned, to name a few.
You're missing a word here: "In attempt"
And why does he need to go through all these places for a weapon? I can buy a gun on any street corner in Brooklyn, why is he having such a hard time?
Pulled into this quest are two key characters, Rebecca Strober and Thede Martone. After inexplicably entering comatose states, Rebecca and Thede become part of the realm between life and death. The two of them pursue Adierenor, who is unaware of their presence, all the while falling in love with each other. Without fully understanding why, Rebecca and Thede have been enlisted in stopping the angel’s unholy mission. Ultimately, they must confront humanity’s true nature and help an angel of God reconcile his faith in mankind—before he delivers the world to doom.
What the hell happened to Marie? If you start your query letter with a character, I assume s/he is the main character. If Marie is not the main character you need to start someplace else.
I am aware that a 120,000-word story is a bit lengthy for a first novel—however, I’ve noticed that angels as protagonists (or antagonists, depending on whether said angel is “fallen”) are on the rise, seen in recent book titles such as Angelology by Danielle Trussoni and Anne Rice’s Songs of the Seraphim series.
Don't excuse your word length. If you have 120K, you have it. And how popular angel books are don't have anything to do with word count. What you mean here most likely is that you've noticed that these popular angel books are longer than the norm. But, you still don't need to say it.
I have published several articles in (redacted) as well as authored a document solicited for inclusion in a manuscript under review for publication, (redacted)
I don't have any sense of the actual story here. You haven't given us a sense of the stakes, or why we should care about the protagonist. In fact, I'm not actually sure who the protagonist is.